The Central Lowlands is a region of rolling hills and plains, with some areas of rugged terrain. The region is drained by the Mississippi River and its tributaries, and the Great Lakes. The climate of the Central Lowlands is continental, with hot summers and cold winters.
The Central Lowlands are a major agricultural region, and they produce a variety of crops, including corn, soybeans, and wheat. The region is also home to significant deposits of coal and other minerals. The Central Lowlands are a major transportation hub, and they are served by a network of highways, railroads, and airports.