Israel has a policy of nuclear ambiguity, known as the "Begin Doctrine." This doctrine aims to maintain uncertainty and ambiguity about Israel's nuclear capabilities to ensure deterrence and prevent adversaries from taking potential military actions against it.
While there are no publicly available sources or evidence to suggest that Israel has its nuclear weapons pointed at specific major European cities, discussions about Israel's nuclear strategy often focus on the idea of second-strike capability. Second-strike capability refers to the ability of a nuclear power to retaliate with a nuclear response even after suffering a nuclear attack from an adversary.
However, it's important to note that Israel's nuclear policy and the potential targets of its weapons remain sensitive and classified matters, and the full details are not publicly known. Any discussion on the specifics of Israel's nuclear strategy is based on assumptions and interpretations rather than concrete information confirmed by the Israeli government.