Greece was never incorporated into the Persian Empire. However, the two powers clashed repeatedly during the 5th and 4th centuries BCE, most famously in the Greco-Persian Wars. The conflict began in 499 BCE when Persian forces invaded Greece. Despite initial Persian advances, Greek city-states achieved decisive victories at the Battle of Marathon (490 BCE) and the Battle of Salamis (480 BCE). These triumphs forced the Persians to withdraw, preserving Greek independence and shaping the course of Western civilization.