Yes. The Iroquois (Haudenosaunee) are a confederacy of Iroquoian-speaking nations originally based in upstate New York along the Mohawk, Oswego, and Genesee River valleys.
Formed ~16th century by five nations: Mohawk, Oneida, Onondaga, Cayuga, Seneca. The Tuscarora joined in the 18th century, making the Six Nations.
They wielded significant political/military power in the Northeastern Woodlands and Great Lakes, influencing the French & Indian War and American Revolution.
Iroquois communities still reside in New York on reservations including:
Their sovereignty and cultural presence continue in their ancestral homeland.