Driving Distance: Atlanta, GA to Carthage, MS
Distance: ~261 miles (420 km)
Drive time: ~4 hours 15 minutes (normal traffic)
Primary Route
- I-20 West from Atlanta → Birmingham, AL
- I-22 West (Corridor X) from Birmingham → Tupelo, MS
- US-45 South / MS-25 South from Tupelo → Carthage
Alternative: I-20 W all the way to Jackson, MS, then US-49 N to Carthage (~285 mi, 4h 30m). I-22 is shorter and faster.
Traffic Notes
- Birmingham I-20/59 interchange: rush hour delays.
- I-22 is mostly 4-lane, 70 mph limit, light traffic.