The southernmost land boundary of the United States is the international border with Mexico.
The boundary follows the Rio Grande (Río Bravo) for ~1,250 miles, then cuts west overland through deserts, mountains (Chihuahuan, Sonoran), and urban areas (San Diego, El Paso, Laredo, Brownsville).
It is the world's most crossed land border (~350 million legal crossings/year pre-pandemic), vital for trade (USMCA), migration, and binational communities.