The Five Largest Cities in Kentucky by Population

1. Louisville – 617,002
2. Lexington – 322,570
3. Bowling Green – 67,594
4. Owensboro – 57,265
5. Covington – 40,640

Figures based on latest U.S. Census Bureau estimates. Louisville dominates as the state's primary metropolitan hub, while Lexington serves as the heart of the Bluegrass region.