Hawaii is the sole US state not part of the contiguous United States (the "Lower 48").
Contiguous = sharing a border. The 48 contiguous states all touch at least one other state, forming a single connected landmass bordered by Canada (north) and Mexico (south).
Alaska borders Canada—so it's part of continental North America but not the contiguous US. "Continental US" = 49 states (incl. Alaska). "Contiguous US" = 48 states. Hawaii is neither.
Shipping costs, federal programs (e.g., Jones Act), military strategy (INDOPACOM), time zones, biodiversity (endemic species), cultural distinctness. Hawaii's isolation shapes everything from grocery prices to energy policy.