Driving time: Approximately 25 hours without accounting for stops
Route:
1. Take Interstate 10 (I-10) east from Los Angeles.
2. Follow I-10 through Arizona and New Mexico.
3. Continue on I-10 through Texas and Louisiana.
4. Take Exit 60 in Mississippi to merge onto Interstate 20 (I-20) east.
5. Follow I-20 east to Opelika, Alabama.