Depending on traffic conditions, the drive time between these two cities can vary. During rush hour (typically between 7:00 AM and 9:00 AM, and between 4:00 PM and 6:00 PM), it can take anywhere from 30 to 60 minutes to drive from Gaithersburg to Bethesda. Outside of rush hour, the drive time is usually between 20 and 30 minutes.