There is no driving route between Virginia (USA) and Accra, Ghana. The Atlantic Ocean separates the two locations by roughly 5,000 miles (8,000 km) as the crow flies.
Travel requires a flight. Typical itineraries connect through major hubs such as New York (JFK), Atlanta, London, or Istanbul, with total travel times ranging from 14 to 20+ hours depending on layovers.
If you need the straight-line (great-circle) distance for planning purposes, it’s approximately 5,100 miles (8,200 km) from the Washington, D.C. area to Accra.