The term "St. Lawrence Freeway" is not standard, but it likely refers to Highway 401—officially the Macdonald-Cartier Freeway—which runs parallel to the St. Lawrence River across southern Ontario. It is a Canadian highway, not a joint US-Canada project.
The St. Lawrence Seaway (opened 1959) is a binational project—a system of locks, canals, and channels allowing ocean-going vessels to travel from the Atlantic to the Great Lakes. Jointly managed by the St. Lawrence Seaway Management Corporation (Canada) and the Great Lakes St. Lawrence Seaway Development Corporation (USA).
So while the highway (401) is purely Canadian, the seaway is a celebrated US-Canada engineering and diplomatic achievement.