- Frequent natural disasters, such as cyclones and droughts, that caused significant damage to the colony and made it difficult to maintain.
- Difficulty maintaining control of the island's population, which included enslaved people of various ethnicities, as well as conflicts with the indigenous Mauritian people.
- Growing competition and conflict with other European powers, particularly the French and the British, who were also vying for control of Indian Ocean routes and territories.
- Limited economic viability, as the Dutch were unable to establish a thriving economy on the island due to its limited resources and geographical isolation.