The Labrador Sea's eastern boundary is defined by Greenland's western coast—specifically, the westernmost points of Greenland's landmass.
The Labrador Sea is a marginal sea of the North Atlantic and a critical site for deep water formation. Cold, saline water sinks here, driving the Atlantic Meridional Overturning Circulation (AMOC)—the "global conveyor belt" regulating climate.
Thule Air Base (Pituffik Space Base) on northwest Greenland monitors Arctic approaches. The Labrador Sea-Greenland margin is a climate change sentinel region—freshwater influx from melting ice threatens AMOC stability.