Does the Mississippi River Run Through the Ozark Mountains?

No Direct Passage

The Mississippi River does not flow through the Ozark Mountains. Instead, it travels primarily through the central United States, draining the vast Mississippi River Basin.

Geographic Relationship

The Ozark Mountains are a major highland region in the south-central U.S., covering parts of Missouri, Arkansas, and Oklahoma. The Mississippi River runs along the eastern edge of this mountain range in some areas, but it does not cut through the interior of the Ozarks.