Yes. The Neuse River has yielded placer gold for centuries. Most gold occurs as placer deposits—concentrations of heavy minerals in river sediments—though hard-rock deposits exist in the basin. Historic mining dates to the 18th century; active operations continue today.
Prospectors need a permit from the NC Department of Environmental Quality, knowledge of state regulations, and basic equipment (pan, sluice, or dredge). Methods include panning, sluicing, and dredging. Research and compliance are essential before searching.