Research flights on different airlines. Websites such as Fly.com and Cheaptickets.com can save you both money and energy by viewing many airlines' flight deals simultaneously. You may want to note that fares to Santiago may be cheapest from April-May and September-October since it's the low season.
Look for flights that arrive in the morning. This will give you time to get acclimated to the city during your first day. It also allows you to find your way around during daylight hours so you will feel more comfortable exploring.
Book your flight and print your itinerary.
Research different hotels in Santiago. Websites such as Expedia.com or Hotels.com can be helpful resources in determining where you would like to stay. Whether you want to be close to Sanhattan or Santa Lucía, you should be able to find a hotel near your desired location. In addition, you can search by star value and amenities, so these websites make it easy to find what you want.
See if your preferred hotel has availability during the dates of your trip. Be aware that holidays and special events can effect availability at certain hotels.
Book your hotel. Make note of check-in and check-out times.
Create a packing list. This will ensure that you don't forget anything when it comes time for you to leave. Many things tend to be forgotten during the stages of pre-trip excitement, so it is advisable to start your list well in advance. In addition, be sure to take note of what time of year you are visiting when planning your packing list. Spring (September-November) is mild, while summer (December-February) tends to be very hot and dry.
Pack your suitcase. Weigh it to make sure that it does not exceed your airline's weight limits.
Attach a luggage tag to your suitcase. This makes it easy to identify it at the airport upon arrival.