Actress in the Lyrica Commercial: Jessica Rothe

The woman featured in Pfizer's Lyrica (pregabalin) commercials is Jessica Rothe, an American actress born May 28, 1987.

Career Highlights

  • Breakthrough: Tree Gelbman in Happy Death Day (2017) and Happy Death Day 2U (2019)
  • La La Land (2016): Alexis, Mia's roommate
  • Valley Girl (2020): Julie Richman (lead)
  • Utopia (2020, Amazon): Samantha
  • Body Brokers (2021): Utah
  • Theatre: Spring Awakening (national tour), The Crucible

About the Lyrica Campaign

Rothe appears in the "Lyrica: Life in Focus" DTC (direct-to-consumer) campaign, portraying a woman managing fibromyalgia/neuropathic pain while pursuing creative passions. The ads emphasize functional improvement—painting, hiking, social connection—rather than just symptom reduction.

Note on Pharmaceutical Advertising

Actor portrayals in drug ads are performances, not patient testimonials. Always consult healthcare providers for medical decisions. Lyrica carries risks (dizziness, edema, weight gain, dependence potential) requiring professional evaluation.

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