Where Do Most People Live in Wyoming? The Southern Tier

Wyoming’s population (~580K) clusters in the southern and central corridors along I-80 and I-25. The three largest cities anchor this zone:

• Cheyenne (capital, ~65K) – southeast corner
• Casper (~58K) – central
• Laramie (~32K) – west of Cheyenne

Jackson (~10K) is a notable western outlier (tourism/gateway to Grand Teton/Yellowstone). The northern and eastern plains remain sparsely settled—ranching, energy, and public lands dominate.