Five Key Interstate Highways Crossing Illinois
- Interstate 80 – Runs east-west across the northern part of the state, connecting Chicago to the Quad Cities.
- Interstate 57 – Runs north-south through the center, connecting Chicago to southern Illinois and Missouri.
- Interstate 72 – Runs east-west across the central part, connecting Springfield to Champaign and Decatur.
- Interstate 290 – A beltway around the western suburbs of Chicago.
- Interstate 39 – Runs north-south through the western part, connecting Rockford to Bloomington and Springfield.
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