What are the 5 major highways in illinois?

- Runs east-west across the northern part of the state, connecting Chicago to the Quad Cities.

2. Interstate 57

- Runs north-south through the center of the state, connecting Chicago to southern Illinois and Missouri.

3. Interstate 72

- Runs east-west across the central part of the state, connecting Springfield to Champaign and Decatur.

4. Interstate 290

- A beltway around the western suburbs of Chicago.

5. Interstate 39

- Runs north-south through the western part of the state, connecting Rockford to Bloomington and Springfield.