What is the last train from Manchester to London on a Saturday?

According to National Rail, the last train from Manchester Piccadilly to London Euston on a Saturday departs at 23:00, arriving at 02:06 the next morning. However, it's always a good idea to check the latest train times and schedules on the National Rail website or through your preferred travel app, as they may be subject to change due to various factors such as track maintenance or special events.