The road distance from Mobile, AL to Walt Disney World (Orlando), FL is approximately 365 miles (587 km).
5.5–6.5 hours without heavy traffic. Add time for stops, Orlando congestion, and Disney parking/tram.
Fly Mobile (MOB) → Orlando (MCO): ~1h 20m nonstop (limited); or connect via ATL/CLT. Often faster door-to-door.