U.S. Route 22 stretches from east to west and runs from Ohio to New Jersey. In Pennsylvania, Route 22 is called the William Penn Highway and travels approximately 319 miles between West Virginia through the suburbs of Pittsburgh and on to Easton at the New Jersey state line. The Lehigh Valley Thruway is a 24-mile long part of the route and passes through a series of highly dangerous curves that have been locally termed the "Cemetery Curve." The Lehigh Valley Thruway runs from Upper Macungie Township to Hanover Township north to the LVI Airport. Speed limits are lowered to 45 miles per hour and dips to 35 mph at the sharpest bend.
This approximately 96-mile stretch of state highway runs north to south and is located in central Pennsylvania. At the south end, it continues into Maryland as Route 165; the terminus in the north is at Pennsylvania Route 75 near Port Royal. Route 74 begins in Juniata County, and there are at least five "S" curves along the way. The route then travels through Perry County. There is an extremely sharp and dangerous "S" curve near the Perry-Cumberland county line as it crosses the Blue Mountain.
Pennsylvania Route 447 is approximately 26 miles long running north to south from the Poconos, terminating at U.S. Route 209 in the south and at Pennsylvania Routes 191 and 507 in Greene Township in the north. In Price Township, Route 447 passes through mountainous territory, and it is in this area that some of the most dangerous curves on the route can be found.
Situated near Penn Hills outside of Pittsburgh, Frankstown Road is one of the most dangerous roads in Western Pennsylvania. According to the District 11 2008 High Crash Locations report, there were 77 crashes and three fatal accidents from 2003 to 2007 on this curvy road.