The Greyhound Bus company is the most widely used public bus transportation system in North America, according to Greyhound. The company has a regularly scheduled bus route from Raleigh that leaves roughly every three hours. The price for a one-way ticket is $79, as of October 2010.
Depending on the time you choose to depart, there are any number of stops you make along the way, and some require transfers. Common stops are in Richmond, Virginia, Baltimore, Maryland, and Newark, New Jersey, with the most common place of transfer being in Virginia. The total trip time is about 10 hours but depends on the number of stops.
Sky Express, operated out of North Carolina, declares its goal to be a convenient, comfortable, safe and cost-effective bus transportation environment for everyone. On Sky Express, the one-way price for a ticket from Raleigh to New York is $40 and the trip takes about 8.5 hours.
Check the website for time schedules as they vary during the year. The address for catching the bus out of Raleigh is 1253 Buck Jones Road, and the address where you will be dropped off in New York is 59 Canal St. or on Madison Avenue, which is in New York's Chinatown district.
Holiday Tours is a bus charter company that operates out of Raleigh, offering trips to New York City. Though the price depends on a number of factors and will be significantly more than a single bus ticket, it offers competitive rates for special events in which you need a chartered bus. The company can organize all aspects of your group tour to New York so you can focus on the trip. Chartered bus tours are perfect for large groups, business trips or long-distance sports travel.