Eschew technology. Cellphones, computers and other devices can frequently keep you plugged in to the outside world regardless of whether you want company. Consider donating your devices to charity, using the funds to help support your isolation endeavor.
Avoid cities, towns, or environments that are highly populated. Think about relocating to places such as northern Canada, Mongolia, or Namibia -- each of these environments features an extremely low population density. Isolation demands keeping encounters with others to a minimum; invest significant research in scouting the locations where run-ins are seldom.
Consider becoming a hermit. Existing outside of society, hermits practice isolation, sometimes self-sufficiently, and frequently in conjunction with a religious practice. Spirituality is not an essential component of a hermit lifestyle; rather, you must choose to appreciate the opportunity for self-reflection and nonconformity that could result from such a life.
Glean insight from examples of isolation in art and literature. The Zen Poetics of Ryokan, "Solitude" by Guy de Maupassant, and "The Mad Monk" by Samuel Taylor Coleridge demonstrate artistic interpretations of isolation and could provide ideas for your own experience.