What is the best route to drive from Los Angeles Philadelphia?

- Get on I-10 W from S Hill St

- Continue on I-10 W to San Pedro

- Take CA-91 W to I-15 N in Riverside County

- Follow I-15 N and I-40 E and I-25 N and I-76 E to Girard Ave in Philadelphia

The total distance of this route is 2,793 miles and the estimated driving time is 43 hours and 55 minutes.