How long does take to drive los angeles from Laredo tx?

Laredo, TX is located approximately 1,350 miles from Los Angeles, CA. Depending on the route you take, it can take anywhere from 20 to 24 hours to drive from Laredo to Los Angeles. The most direct route is to take Interstate 10 West from Laredo to Los Angeles, which takes about 20 hours of driving time. However, you may encounter traffic congestion and delays, so it's best to allow for more time.