Distance from Cleveland to the Florida Keys
Cleveland, OH → Key West, FL: ~1,200 miles (1,930 km) by road.
Primary Route (I-75 S / I-95 S)
- Cleveland → Cincinnati (I-71) → Lexington → Knoxville → Atlanta (I-75) → Macon → Lake City → Orlando → Florida's Turnpike → US-1 to Key West.
- Time: 19–20 hours driving (no stops).
Alternative (I-77 S / I-26 E / I-95 S)
- Cleveland → Charleston, WV → Columbia, SC → Savannah → Jacksonville → I-95 to Keys.
- ~1,250 miles, 20–21 hours.
Real-world: 2.5–3 days with rest, meals, sleep. Fly CLE→EYW/MCO (3–4 hrs) + drive.
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