Choose your transportation. Two trains a day operate between Grenada and Madrid, one in the morning and one in the evening. Iberia Airlines, Spainair and Air Europa all operate several flights a day between between the two cities. As of late 2010, a round trip fare by train or plane cost just under $200. Traveling to Madrid by car will take you about five hours on the E-5 highway, though first time visitors to Madrid may be discouraged by the difficult parking and driving conditions.
Book your trip. Train and plane tickets may be booked online in advance. Train tickets may be purchased through the Rail Europe website, or directly from Renfe, the Spanish national railway. Plane tickets may be purchased online directly from the airlines. If you plan on driving, Easy Car and Rent Spain are two local options. Both offer online reservations and have offices in Grenada and Madrid.
Enjoy the trip. Traveling by train or car will give you the opportunity to see and experience the beautiful Spanish mountains. Relax and enjoy yourself.