- John Middleton (estimated net worth: $2.4 billion)
- James Middleton (estimated net worth: $1.6 billion)
- William Middleton (estimated net worth: $1.4 billion)
- Thomas Middleton (estimated net worth: $1.2 billion)
- Henry Middleton (estimated net worth: $1 billion)
- George Middleton (estimated net worth: $950 million)
- Samuel Middleton (estimated net worth: $900 million)
- Richard Middleton (estimated net worth: $850 million)
- Charles Middleton (estimated net worth: $800 million)
- David Middleton (estimated net worth: $750 million)
Please note that this list may be outdated, and there may be changes in the rankings since the data was last updated. Additionally, the estimated net worth figures may vary depending on different sources and methodologies used.