Are there any mountain ranges near the Mississippi river?

There are no major mountain ranges near the Mississippi River. The closest mountain ranges to the Mississippi River are the Ozark Mountains, located in Missouri and Arkansas, and the Appalachian Mountains, located in the eastern United States. The Ozark Mountains are about 100 miles (160 km) west of the Mississippi River, and the Appalachian Mountains are about 500 miles (800 km) east of the Mississippi River.