The Ohio River is a naturally occurring river—not a man-made canal or political acquisition "added" to the United States. It flows 981 miles (1,579 km) from Pittsburgh, PA (confluence of Allegheny & Monongahela) to Cairo, IL, where it joins the Mississippi.
Historical Context:
The river became a U.S. boundary and transportation artery through treaties and settlement—but the river itself was never "added." It's a geographic feature that shaped history.