Major Ohio Cities North of the Ohio River

The **Ohio River** forms Ohio's **entire southern and eastern border** (451 miles / 726 km). **All of Ohio lies north of the Ohio River**—it's the state's southern boundary. Therefore, **every major Ohio city is north of the Ohio River**.

However, if the question means **large cities in the *northern part* of Ohio** (near Lake Erie), the three largest are:

1. Cleveland (Cuyahoga County) — **Population ~370,000** (metro 2.1M). **Lake Erie port, healthcare, manufacturing, Rock Hall.**
2. Akron (Summit County) — **~190,000** (metro 700K). **Polymer/rubber capital, Goodyear, Firestone, University of Akron.**
3. Toledo (Lucas County) — **~270,000** (metro 600K). **Lake Erie/ Maumee Bay port, Jeep, glass, solar, University of Toledo.**

Other large northern Ohio cities: **Lorain, Elyria, Parma, Canton, Youngstown, Mansfield, Sandusky, Fremont, Port Clinton.**

Clarification: **Cincinnati, Portsmouth, Marietta, Steubenville** are **on the Ohio River** (north bank). **No Ohio city is south of it**—that's Kentucky/West Virginia.