The Mediterranean Sea dwarfs North America's Great Lakes—covering 2.5 million km² versus the Great Lakes' combined 246,000 km². That's roughly a 10:1 ratio in surface area.
The Mediterranean is a true sea—connected to the Atlantic, spanning 4,000 km east-west, with tectonic origins creating deep basins. The Great Lakes are glacial scour depressions filled with freshwater, relatively shallow and entirely landlocked.
The Mediterranean drives regional climate, hosts 17,000+ marine species, and has been a civilizational crossroads for millennia. The Great Lakes hold 21% of Earth's surface freshwater, support 34 million people, and power a massive industrial economy.
While the Mediterranean is ~10× larger in area, the Great Lakes contain 84% of North America's surface freshwater—a resource of incalculable value.