The Pacific Region of the United States (as defined by the Census Bureau) comprises five states: California, Oregon, Washington, Alaska, and Hawaii.
By a massive margin, California has the largest population:
California alone accounts for ~75% of the Pacific Region's total population (~53M). Its dominance drives the region's economy (5th largest globally), culture, politics, and congressional representation (52 House seats).
Note: "Pacific Region" definitions vary. Census Bureau: CA, OR, WA, AK, HI. Some economic/geographic definitions include AZ, NV. By any definition, CA is #1.