The road distance between Ocala, Florida and Orlando, Florida is approximately 65 miles (105 km) via I-75 South to Florida's Turnpike or I-4 East. Typical drive time is 1 hour 15 minutes to 1 hour 30 minutes, depending on traffic, construction, and exact start/end points.
Both cities lie in Central Florida; Ocala is known for horse farms and natural springs, while Orlando is the theme park capital. The route passes through rolling hill country and the Orlando metro sprawl.