1. Start by heading south on Interstate 75 (I-75) from Flint, Michigan.
2. Continue on I-75 through Ohio and Kentucky, passing cities like Toledo, Dayton, Cincinnati, and Lexington.
3. Stay on I-75 until you reach Knoxville, Tennessee.
4. In Knoxville, take Interstate 40 (I-40) east towards Asheville, North Carolina.
5. Follow I-40 through North Carolina, passing cities like Asheville, Winston-Salem, and Greensboro.
6. Continue on I-40 until you reach Birmingham, Alabama.