Major Highways in Florida: Interstates, Turnpike, U.S. Routes

Florida's highway network centers on three Interstate spines and the Turnpike:

Interstates

• I-4: East-west across central FL (Tampa–Orlando–Daytona–Jacksonville)
• I-95: North-south Atlantic coast (Jacksonville–Miami)
• I-75: North-south western peninsula (Georgia border–Miami via Tampa, Fort Myers); includes Alligator Alley (Everglades)

Toll Road

• Florida's Turnpike (SR 91): Miami–Orlando–Wildwood (north-south); Homestead Extension (SR 821) to Florida City

U.S. Highways

• US 1: Overseas Highway (Key West–Mainland) + coastal route to Georgia
• US 27: Miami–Tallahassee (inland alternative)
• US 41: Tamiami Trail (Miami–Naples–Tampa–Georgia)
• US 98: Gulf Coast (Pensacola–Panama City–Perry–St. Augustine)

Florida has 1,500+ miles of Interstate; tolls on Turnpike, Alligator Alley (I-75), and some bridges (SunPass/E-Pass).