How do you get from Des Moines IA to Sioux City by car?

To get from Des Moines, Iowa to Sioux City by car, take the following steps:

1. Head north on Merle Hay Rd toward Douglas Ave:

- Merge onto I-235 N

- Take exit 109 for E 14th St and merge onto E 14th St

- Merge onto US 6 E at the fork

2. Continue on US-169 N for approximately 193 miles

- Drive through Story County

- Drive through Hamilton County

- Drive through Wright County

- Drive through Hancock County

- Drive through Cerro Gordo County

- Drive through Floyd County

- Drive through Sioux County

3. Take exit 147, continue onto IA-12 E/War Eagle Dr

4. Turn left onto IA-275 W

5. Take the 2nd exit toward Downtown

6. Arrive at Sioux City