1. Grandi Navi Veloci (GNV): This company offers direct ferry trips from Valletta, Malta to Genoa, Italy, with sailings usually operated on a weekly basis. The journey time is approximately 20 hours.
2. Grimaldi Lines: Grimaldi Lines also offers direct ferry services between Valletta and Genoa. The trip duration is approximately 20-24 hours.
3. Virtu Ferries: Virtu Ferries operates a high-speed ferry service from Valletta to Pozzallo, Sicily. From Pozzallo, you can take a train or bus to Genoa. The total travel time using this route is approximately 12-14 hours.
It's worth noting that the frequency and availability of these ferry services can vary depending on the season and demand, so it's recommended to check with the ferry companies directly for the latest schedule and ticket information.