What is the best way from Regina SK to Fort Myers FL?

- Take SK-1/Trans-Canada Hwy West for 1,145 miles

- Merge onto I-29 South for 1,050 miles

- Take I-10 West for 450 miles

- Take I-75 South for 115 miles

Flying (5.5-7 hours + layovers)

- Fly from Regina International Airport (YQR) to Southwest Florida International Airport (RSW) with a layover in Toronto (YYZ), Atlanta (ATL), or Charlotte (CLT).