There is no record of a Prestwould Plantation in Clarksville, Virginia. The historic Prestwould Plantation is located in Chatham, Virginia (Pittsylvania County). Built in the 1790s by Sir Peyton Skipwith, it is one of the best-preserved late-18th-century plantations in the South, featuring original outbuildings, gardens, and family collections. It is a National Historic Landmark open for tours.
If you are researching Prestwould, Chatham is the correct location.