Consult a road map to determine the distance and primary highways to your destination.
Use an Internet mapping site, like Google Maps or MapQuest if you need point-by-point instructions. For a more dedicated travel plan, enter your point of departure and your destination into the route finder at TripIt.com, Rand McNally or AAA Travel, which will alert you to roadworks and delays on major routes.
Plot specific stops on your trip based on your interests, gas consumption or meal times. AAA's travel planner even shows you the current gas prices you'll pass so you know just when to stop for the cheapest highway gas.
E-mail or link your route planner to a friend or travel companion.
Print out all maps and directions before you go. Pack a map that covers the whole distance of your trip, too -- in case you ever find yourself far away from your plotted course.