No nonstop LAX → South America flights exist. All routes connect—typically via Mexico, Panama, or US hubs.
LAX → MEX (Mexico City) → BOG (Bogotá): ~6h 45m total (2h 30m + 4h 15m + layover). ~10h 35m door-to-door with typical 1.5h connection.
| Destination | Best Hub | Typical Time |
|---|---|---|
| Bogotá (BOG) | MEX, PTY | 10–12h |
| Lima (LIM) | PTY, MEX | 11–13h |
| Santiago (SCL) | PTY, ATL | 14–16h |
| São Paulo (GRU) | PTY, IAH | 13–15h |
| Buenos Aires (EZE) | PTY, ATL | 15–17h |
| Rio (GIG) | PTY, IAH | 14–16h |
| Quito (UIO) | PTY, MEX | 10–12h |
Seasonal schedules, visa requirements (Mexico transit visa for some nationalities), weather (Andes fog, Caribbean storms), aircraft (737/320 vs. 787/350). Book 60–90 days out for best fares/connections.