There is no straight-line land route from Gibraltar to Jerusalem. Gibraltar sits at the southwestern tip of Europe's Iberian Peninsula; Jerusalem lies in southwestern Asia. Any journey requires crossing the Mediterranean Sea and traversing multiple countries.
Most travelers fly: Gibraltar (GIB) → Madrid or London → Tel Aviv (TLV), then drive to Jerusalem (~1 hour). Direct flights are rare; connections are typical.
By sea, ferries run from Algeciras (near Gibraltar) to Tangier, then overland through North Africa and the Levant—but this is circuitous and politically complex.