Did a Famous Journey Begin with a Flight Out of San Diego?

The premise that a famous journey started with a flight from San Diego appears to be a misunderstanding. While San Diego has played a pivotal role in aviation history—most notably as the birthplace of Charles Lindbergh's Spirit of St. Louis—Lindbergh's historic 1927 transatlantic flight actually departed from New York's Roosevelt Field. Other notable journeys, such as the first around-the-world flight in 1924, began in Seattle. If you have a specific expedition in mind, providing more details will help clarify its true starting point.