* Vicente Diaz (1898-1982): Chamorro politician and Senator in the Guam Legislature from 1948 to 1962. He was also mayor of Hagåtña, the capital of Guam, from 1963 to 1969.
* Joseph Flores (1916-1988): Chamorro politician and the first native Governor of Guam from 1975 to 1979.
* Angel Santos (1924-1991): Chamorro artist known for his paintings and sculptures depicting Chamorro culture and history.
* Paul M. Calvo (born 1939): Chamorro politician and Governor of Guam from 1995 to 2003.
* Madeleine Bordallo (1933-2019): Chamorro politician and the first woman to serve as Governor of Guam, from 2003 to 2011.
* Michael San Nicolas (born 1981): Chamorro politician and the current Delegate for Guam in the United States House of Representatives, serving since 2019.