* 1764: James Watt patents the steam engine.
* 1769: Nicolas-Joseph Cugnot develops the first automobile.
1770s
* 1776: Jesse Ramsden invents the dividing engine.
* 1777: Antoine Lavoisier develops the metric system.
* 1779: Samuel Crompton invents the spinning mule.
1780s
* 1784: Edmund Cartwright patents the power loom.
* 1785: Jean-François Pilâtre de Rozier and François Laurent d'Arlandes make the first hot air balloon flight.
* 1789: William Herschel discovers Uranus.
1790s
* 1790: Eli Whitney invents the cotton gin.
* 1796: Edward Jenner develops the smallpox vaccine.
* 1799: Alessandro Volta invents the electric battery.
1800s
* 1800: William Herschel discovers infrared radiation.
* 1801: Johann Wilhelm Ritter discovers ultraviolet radiation.
* 1802: Richard Trevithick builds the first successful steam locomotive.
* 1804: Robert Fulton builds the first successful steamboat.
1810s
* 1810: Humphry Davy invents the safety lamp.
* 1816: William Prout proposes the Prout hypothesis, which states that all elements are composed of hydrogen atoms.
* 1819: Johann Wolfgang Döbereiner discovers the triads of elements.
1820s
* 1827: George Stephenson builds the Locomotion, the first steam locomotive to pull a passenger train.
* 1829: Michael Faraday discovers electromagnetic induction.
* 1831: Joseph Henry discovers self-induction.
1830s
* 1833: Samuel Morse invents the telegraph.
* 1834: Charles Babbage proposes the Analytical Engine, a mechanical general-purpose computer.
* 1837: John Deere invents the steel plow.
1840s
* 1844: Samuel Morse sends the first telegraph message.
* 1847: Elias Howe patents the sewing machine.
* 1848: James Nasmyth invents the steam hammer.
1850s
* 1851: The Great Exhibition in London showcases the latest innovations from around the world.
* 1856: Henry Bessemer patents the Bessemer process for making steel.
* 1857: Elisha Otis invents the safety elevator.
1860s
* 1860: John Tyndall discovers the greenhouse effect.
* 1861: James Clerk Maxwell publishes A Dynamical Theory of the Electromagnetic Field, which unifies electricity and magnetism.
* 1869: Dmitri Mendeleev publishes his periodic table of elements.