Consider what you are looking for in a bus tour. You can take a double-decker bus tour in Manhattan. You can take a weeklong tour that will go from Manhattan to Niagara Falls and then south to Washington, D.C. Or you might want to plan an upstate tour in the fall so you can enjoy the colorful foliage. There are even bus-linked wine tours.
The state offers an entirely linked bus system. If you want to tour on your own, you can plan your stops all over the state, getting on and off the bus at your leisure. This offers you the most leeway with trip planning.
New York features a bus for technology-savvy travelers that includes mood-enhancing lights, stadium seating and 40 video screens that you will allow you to enjoy the city in a novel way.
Summer and Christmas are traditionally busy times for tourists in Manhattan as well as in New York's mountainous destinations. By taking advantage of the off-season you can benefit from lower prices and fewer people on your tour.
If you have a large group of people, consider chartering a bus. This will allow you to pick the route with the company as well as give you the freedom of customizing your schedule.