The road distance from Detroit, Michigan to Seattle, Washington spans approximately 2,250 miles (3,625 km). Expect 35–40 hours of pure driving time—typically 4–5 days with realistic stops.
Most direct: Detroit → Chicago (I-94) → Madison → Minneapolis → Billings → Butte → Spokane → Seattle. ~2,300 miles. Crosses Great Plains, Rocky Mountains, Cascades.
Detroit → Toledo → Chicago → Omaha → Cheyenne → Salt Lake City → Boise → Portland → Seattle (I-84). ~2,350 miles. Different scenery: Salt Flats, Columbia River Gorge.
Budget $300–500 fuel (one-way, 25 mpg avg), plus lodging/meals. An epic cross-section of America.